Episode 104: The MitoImmune Method: Rebuild Cellular Energy & Immune Resilience
We are celebrating one year since the release of Optimal You and revisiting the two foundational pillars—energy and immunity—and exploring how they work together through the MitoImmune Method. If you’ve been feeling chronically tired, overwhelmed by stress, constantly sick, or stuck in cycles of burnout, this episode breaks down the real science behind what’s happening inside your body and why your symptoms aren’t random.
Nicole takes you deeper into cellular energy, mitochondrial repair, and immune resilience, highlighting the modern-day stressors that drain vitality: chronic stress, poor sleep, nutrient depletion, inflammation, viral reactivation, and gut dysbiosis. Using a real patient case study, she illustrates how restoring mitochondrial function and calming immune dysregulation creates long-lasting, sustainable health from the inside out.
This episode answers questions like:
“Why am I always tired even after resting?”
“How to fix chronic fatigue naturally”
“What causes a low immune system?”
“Why do I get sick so easily?”
“Best supplements for energy and immunity”
“Signs of adrenal fatigue”
“Foods for mitochondrial health”
You’ll also learn the exact nutrients, habits, and lifestyle strategies that rebuild energy and support balanced immunity, from B vitamins, CoQ10, and iron to nervous system regulation, sleep hygiene, gut support, and mitochondrial repair. By the end, you’ll understand how the MitoImmune Method reconnects the dots between fatigue, immunity, stress, inflammation, and resilience. This episode will leave you with actionable steps to feel clearer, calmer, and more energised every single day.
DISCLAIMER: The content in this podcast and related website is not intended to be a substitute for medical advice. It is not intended to be used to diagnose or treat, instead it is designed to help educate and inspire. Always seek the advice of a professional medical practitioner or qualified health practitioner. Never ignore or disregard advice given to you based on information in this podcast or related website and do not delay in seeking medical advice.
Timestamps:
[00:50] - One Year of Optimal You book
Celebrating one year of Optimal You and reviewing how mitochondrial health and immune resilience have transformed thousands of listeners and patients.
[02:40] - The First Two Pillars of the MitoImmune Method: Energy & Immunity
Breaking down the two-way relationship between energy production and immune function, how imbalance leads to chronic symptoms, and why restoring this connection is the key to reversing burnout, fatigue, and inflammation.
[05:40] - How Energy Production Really Works (Cellular Energy + Mitochondria)
A deep dive into chronic fatigue, low immunity, mitochondrial dysfunction, and why modern stress drains cellular energy.
[12:50] - Nutrition & Lifestyle That Rebuild Mitochondrial Energy
B vitamins, iron, CoQ10, omega-3s, sleep, stress regulation, movement, recovery, and the habits that restore cellular energy and vitality.
[21:00] - Nutrition & Supplements for Immune Balance and Recovery
Vitamin C, vitamin D, zinc, selenium, glutathione, medicinal mushrooms, gut support, and targeted nutrients that regulate immune communication.
[25:10] - How to Rebuild Energy & Immunity With the MitoImmune Method
Science-backed habits, supplements, and lifestyle practices that restore vitality, longevity, and whole-body health through the MitoImmune Method.
“Your body is constantly communicating with you, and when you feel exhausted, foggy, or unable to recover, it’s often a sign that your cellular energy production is under strain. Your mitochondria respond to every stressor you face: chronic stress, poor sleep, inflammation, nutrient depletion, and environmental toxins. When those inputs stack up, your energy output drops.”
Essential learnings from this episode…
Energy and immunity are biologically interconnected. Mitochondrial health directly shapes immune strength, inflammation, recovery, and viral resilience. This “mitoimmune axis” explains why fatigue and low immunity often appear together.
Chronic fatigue is a sign that mitochondrial energy output is diminished by stress, toxins, poor sleep, or nutrient depletion. It is not laziness.
True immune health comes from regulating inflammation, supporting gut health, and restoring nutrient levels, not overstimulation. This reduces autoimmunity, viral reactivation, and chronic illness.
Chronic stress, disrupted sleep, environmental toxins, overtraining, and nutrient-poor diets create oxidative stress and weaken immune defense. Addressing these restores long-term vitality.
Specific nutrients power mitochondrial repair and immune function.
Healing is possible when you support both systems together. Rebuilding mitochondrial function + calming immune dysregulation leads to improved energy, fewer infections, reduced inflammation, and sustainable resilience.
EPISODE 104
Important links & mentions from this episode
FREE Optimal Supplement Guide. Use NICOLE20
Take the FREE MitoImmune Health Assessment
Waitlist for the Goode Health Studio
Check Out our Updated Packages
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